Transcriptional Dynamics Elicited by a Short Pulse of Notch Activation Involves Feed-Forward Regulation by E(spl)/Hes Genes

Dynamic activity of signaling pathways, such as Notch, is vital to achieve correct development and homeostasis. However, most studies assess output many hours or days after initiation of signaling, once the outcome has been consolidated. Here we analyze genome-wide changes in transcript levels, bind...

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Detalles Bibliográficos
Autores principales: Housden, Ben E., Fu, Audrey Q., Krejci, Alena, Bernard, Fred, Fischer, Bettina, Tavaré, Simon, Russell, Steven, Bray, Sarah J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3536677/
https://www.ncbi.nlm.nih.gov/pubmed/23300480
http://dx.doi.org/10.1371/journal.pgen.1003162

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