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Single-Cell and Population NF-κB Dynamic Responses Depend on Lipopolysaccharide Preparation
BACKGROUND: Lipopolysaccharide (LPS), found in the outer membrane of gram-negative bacteria, elicits a strong response from the transcription factor family Nuclear factor (NF)-κB via Toll-like receptor (TLR) 4. The cellular response to lipopolysaccharide varies depending on the source and preparatio...
Autores principales: | Gutschow, Miriam V., Hughey, Jacob J., Ruggero, Nicholas A., Bajar, Bryce T., Valle, Sean D., Covert, Markus W. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3536753/ https://www.ncbi.nlm.nih.gov/pubmed/23301045 http://dx.doi.org/10.1371/journal.pone.0053222 |
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