Synthesis, Antitubercular Activity and Mechanism of Resistance of Highly Effective Thiacetazone Analogues

Defining the pharmacological target(s) of currently used drugs and developing new analogues with greater potency are both important aspects of the search for agents that are effective against drug-sensitive and drug-resistant Mycobacterium tuberculosis. Thiacetazone (TAC) is an anti-tubercular drug...

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Detalles Bibliográficos
Autores principales: Coxon, Geoffrey D., Craig, Derek, Corrales, Rosa Milagros, Vialla, Emilie, Gannoun-Zaki, Laila, Kremer, Laurent
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3536773/
https://www.ncbi.nlm.nih.gov/pubmed/23301038
http://dx.doi.org/10.1371/journal.pone.0053162

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3536773/
https://www.ncbi.nlm.nih.gov/pubmed/23301038
http://dx.doi.org/10.1371/journal.pone.0053162

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