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Synthesis, Antitubercular Activity and Mechanism of Resistance of Highly Effective Thiacetazone Analogues
Defining the pharmacological target(s) of currently used drugs and developing new analogues with greater potency are both important aspects of the search for agents that are effective against drug-sensitive and drug-resistant Mycobacterium tuberculosis. Thiacetazone (TAC) is an anti-tubercular drug...
| Autores principales: | , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Public Library of Science
2013
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3536773/ https://www.ncbi.nlm.nih.gov/pubmed/23301038 http://dx.doi.org/10.1371/journal.pone.0053162 |