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ERG Transcriptional Networks in Primary Acute Leukemia Cells Implicate a Role for ERG in Deregulated Kinase Signaling

High expression of the E26 transforming sequence related gene (ERG) is associated with poor prognosis in a subgroup of leukemia patients with acute myeloid (AML) and acute T-lymphoblastic leukemia (T-ALL). In a previous study we proposed that ERG overexpression may deregulate several signaling casca...

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Detalles Bibliográficos
Autores principales: Bock, Juliane, Mochmann, Liliana H., Schlee, Cornelia, Farhadi-Sartangi, Nasrin, Göllner, Stefanie, Müller-Tidow, Carsten, Baldus, Claudia D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3536782/
https://www.ncbi.nlm.nih.gov/pubmed/23300998
http://dx.doi.org/10.1371/journal.pone.0052872