Reductive whole-cell biotransformation with Corynebacterium glutamicum: improvement of NADPH generation from glucose by a cyclized pentose phosphate pathway using pfkA and gapA deletion mutants

In this study, the potential of Corynebacterium glutamicum for reductive whole-cell biotransformation is shown. The NADPH-dependent reduction of the prochiral methyl acetoacetate (MAA) to the chiral (R)-methyl 3-hydroxybutyrate (MHB) by an alcohol dehydrogenase from Lactobacillus brevis (Lbadh) was...

Descripción completa

Detalles Bibliográficos
Autores principales: Siedler, Solvej, Lindner, Steffen N., Bringer, Stephanie, Wendisch, Volker F., Bott, Michael
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer-Verlag 2012
Materias:
Biotechnological Products and Process Engineering
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3536970/
https://www.ncbi.nlm.nih.gov/pubmed/22851018
http://dx.doi.org/10.1007/s00253-012-4314-7

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3536970/
https://www.ncbi.nlm.nih.gov/pubmed/22851018
http://dx.doi.org/10.1007/s00253-012-4314-7

Ejemplares similares