Small-molecule inhibitors of the cystic fibrosis transmembrane conductance regulator increase pancreatic endocrine cell development in rat and mouse

AIMS/HYPOTHESIS: The main objective of this work was to discover new drugs that can activate the differentiation of multipotent pancreatic progenitors into endocrine cells. METHODS: In vitro experiments were performed using fetal pancreatic explants from rats and mice. In this assay, we examined the...

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Detalles Bibliográficos
Autores principales: Zertal-Zidani, S., Busiah, K., Edelman, A., Polak, M., Scharfmann, R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer-Verlag 2012
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3536988/
https://www.ncbi.nlm.nih.gov/pubmed/23178930
http://dx.doi.org/10.1007/s00125-012-2778-8

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3536988/
https://www.ncbi.nlm.nih.gov/pubmed/23178930
http://dx.doi.org/10.1007/s00125-012-2778-8

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