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Adaptive changes of human islets to an obesogenic environment in the mouse

AIMS/HYPOTHESIS: In this study, we used an immunodeficient mouse model to explore, in vivo, the longitudinal adaptation of human islets to an obesogenic environment. METHODS: Non-diabetic Rag2 (–/–) mice (n = 61) were transplanted with human islets (400 islet equivalents [IEQ]) from six pancreases:...

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Detalles Bibliográficos
Autores principales:	Gargani, S., Thévenet, J., Yuan, J. E., Lefebvre, B., Delalleau, N., Gmyr, V., Hubert, T., Duhamel, A., Pattou, F., Kerr-Conte, J.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Springer-Verlag 2012
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3536990/ https://www.ncbi.nlm.nih.gov/pubmed/23192693 http://dx.doi.org/10.1007/s00125-012-2775-y

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