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Increase in Serum Ca(2+/)Mg(2+) Ratio Promotes Proliferation of Prostate Cancer Cells by Activating TRPM7 Channels
TRPM7 is a novel magnesium-nucleotide-regulated metal current (MagNuM) channel that is regulated by serum Mg(2+) concentrations. Changes in Mg(2+) concentration have been shown to alter cell proliferation in various cells; however, the mechanism and the ion channel(s) involved have not yet been iden...
Autores principales: | , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Society for Biochemistry and Molecular Biology
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3537020/ https://www.ncbi.nlm.nih.gov/pubmed/23168410 http://dx.doi.org/10.1074/jbc.M112.393918 |