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Increase in Serum Ca(2+/)Mg(2+) Ratio Promotes Proliferation of Prostate Cancer Cells by Activating TRPM7 Channels

TRPM7 is a novel magnesium-nucleotide-regulated metal current (MagNuM) channel that is regulated by serum Mg(2+) concentrations. Changes in Mg(2+) concentration have been shown to alter cell proliferation in various cells; however, the mechanism and the ion channel(s) involved have not yet been iden...

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Detalles Bibliográficos
Autores principales:	Sun, Yuyang, Selvaraj, Senthil, Varma, Archana, Derry, Susan, Sahmoun, Abe E., Singh, Brij B.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Society for Biochemistry and Molecular Biology 2013
Materias:	Signal Transduction
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3537020/ https://www.ncbi.nlm.nih.gov/pubmed/23168410 http://dx.doi.org/10.1074/jbc.M112.393918

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