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F-box and Leucine-rich Repeat Protein 5 (FBXL5) Is Required for Maintenance of Cellular and Systemic Iron Homeostasis

Maintenance of cellular iron homeostasis requires post-transcriptional regulation of iron metabolism genes by iron regulatory protein 2 (IRP2). The hemerythrin-like domain of F-box and leucine-rich repeat protein 5 (FBXL5), an E3 ubiquitin ligase subunit, senses iron and oxygen availability and faci...

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Detalles Bibliográficos
Autores principales:	Ruiz, Julio C., Walker, Scott D., Anderson, Sheila A., Eisenstein, Richard S., Bruick, Richard K.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Society for Biochemistry and Molecular Biology 2013
Materias:	Cell Biology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3537052/ https://www.ncbi.nlm.nih.gov/pubmed/23135277 http://dx.doi.org/10.1074/jbc.M112.426171

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