BATF-JUN is critical for IRF4-mediated transcription in T cells

Interferon regulatory factor 4 (IRF4) is an IRF family transcription factor with critical roles in lymphoid development and in regulating the immune response(1,2). IRF4 binds DNA weakly due to a C-terminal auto-inhibitory domain, but cooperative binding with factors such as PU.1 or SPIB in B cells i...

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Detalles Bibliográficos
Autores principales: Li, Peng, Spolski, Rosanne, Liao, Wei, Wang, Lu, Murphy, Theresa L., Murphy, Kenneth M., Leonard, Warren J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2012
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3537508/
https://www.ncbi.nlm.nih.gov/pubmed/22992523
http://dx.doi.org/10.1038/nature11530

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3537508/
https://www.ncbi.nlm.nih.gov/pubmed/22992523
http://dx.doi.org/10.1038/nature11530

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