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Enhancement of radiation response with bevacizumab

BACKGROUND: Vascular endothelial growth factor (VEGF) plays a critical role in tumor angiogenesis. Bevacizumab is a humanized monoclonal antibody that neutralizes VEGF. We examined the impact on radiation response by blocking VEGF signaling with bevacizumab. METHODS: Human umbilical vein endothelial...

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Detalles Bibliográficos
Autores principales: Hoang, Tien, Huang, Shyhmin, Armstrong, Eric, Eickhoff, Jens C, Harari, Paul M
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3537546/
https://www.ncbi.nlm.nih.gov/pubmed/22538017
http://dx.doi.org/10.1186/1756-9966-31-37