CRISPR transcript processing: a mechanism for generating a large number of small interfering RNAs

BACKGROUND: CRISPR/Cas (Clustered Regularly Interspaced Short Palindromic Repeats/CRISPR associated sequences) is a recently discovered prokaryotic defense system against foreign DNA, including viruses and plasmids. CRISPR cassette is transcribed as a continuous transcript (pre-crRNA), which is proc...

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Detalles Bibliográficos
Autores principales: Djordjevic, Marko, Djordjevic, Magdalena, Severinov, Konstantin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2012
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3537551/
https://www.ncbi.nlm.nih.gov/pubmed/22849651
http://dx.doi.org/10.1186/1745-6150-7-24

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