An inverse metabolic engineering approach for the design of an improved host platform for over-expression of recombinant proteins in Escherichia coli

BACKGROUND: A useful goal for metabolic engineering would be to generate non-growing but metabolically active quiescent cells which would divert the metabolic fluxes towards product formation rather than growth. However, for products like recombinant proteins, which are intricately coupled to the gr...

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Detalles Bibliográficos
Autores principales: Ghosh, Chaitali, Gupta, Rashmi, Mukherjee, Krishna Jyoti
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2012
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3537655/
https://www.ncbi.nlm.nih.gov/pubmed/22759404
http://dx.doi.org/10.1186/1475-2859-11-93

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3537655/
https://www.ncbi.nlm.nih.gov/pubmed/22759404
http://dx.doi.org/10.1186/1475-2859-11-93

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