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An inverse metabolic engineering approach for the design of an improved host platform for over-expression of recombinant proteins in Escherichia coli
BACKGROUND: A useful goal for metabolic engineering would be to generate non-growing but metabolically active quiescent cells which would divert the metabolic fluxes towards product formation rather than growth. However, for products like recombinant proteins, which are intricately coupled to the gr...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
BioMed Central
2012
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3537655/ https://www.ncbi.nlm.nih.gov/pubmed/22759404 http://dx.doi.org/10.1186/1475-2859-11-93 |