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MLEP: an R package for exploring the maximum likelihood estimates of penetrance parameters

BACKGROUND: Linkage analysis is a useful tool for detecting genetic variants that regulate a trait of interest, especially genes associated with a given disease. Although penetrance parameters play an important role in determining gene location, they are assigned arbitrary values according to the re...

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Detalles Bibliográficos
Autor principal: Sugaya, Yuki
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3537736/
https://www.ncbi.nlm.nih.gov/pubmed/22929166
http://dx.doi.org/10.1186/1756-0500-5-465