Profound tumor-specific Th2 bias in patients with malignant glioma

BACKGROUND: Vaccination against tumor-associated antigens is one promising approach to immunotherapy against malignant gliomas. While previous vaccine efforts have focused exclusively on HLA class I-restricted peptides, class II-restricted peptides are necessary to induce CD4(+) helper T cells and s...

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Detalles Bibliográficos
Autores principales: Shimato, Shinji, Maier, Lisa M, Maier, Richard, Bruce, Jeffrey N, Anderson, Richard CE, Anderson, David E
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2012
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3537750/
https://www.ncbi.nlm.nih.gov/pubmed/23186108
http://dx.doi.org/10.1186/1471-2407-12-561

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