Inhibition of Platelet-Derived Growth Factor Receptor Signaling Regulates Oct4 and Nanog Expression, Cell Shape, and Mesenchymal Stem Cell Potency

Defining the signaling mechanisms that regulate the fate of adult stem cells is an essential step toward their use in regenerative medicine. Platelet-derived growth factor receptor (PDGFR) signaling plays a crucial role in specifying mesenchymal stem cell (MSC) commitment to mesenchymal lineages. Ba...

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Detalles Bibliográficos
Autores principales: Ball, Stephen G, Shuttleworth, Adrian, Kielty, Cay M
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Wiley Subscription Services, Inc., A Wiley Company 2012
Materias:
Original Research: Tissue-Specific Stem Cells
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3537888/
https://www.ncbi.nlm.nih.gov/pubmed/22213560
http://dx.doi.org/10.1002/stem.1015

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3537888/
https://www.ncbi.nlm.nih.gov/pubmed/22213560
http://dx.doi.org/10.1002/stem.1015

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