Cargando…

Photoreceptor rescue of pigment epithelium-derived factor-impregnated nanoparticles in Royal College of Surgeons rats

PURPOSE: To investigate the protective effect of intravitreal injection of pigment epithelium-derived factor-impregnated nanoparticles (PEDF-NPs) against photoreceptor degeneration in Royal College of Surgeons (RCS) rats. METHODS: Three-week-old RCS rats received an intravitreal injection of PBS, bl...

Descripción completa

Detalles Bibliográficos
Autores principales:	Akiyama, Goichi, Sakai, Tsutomu, Kuno, Noriyuki, Kimura, Erika, Okano, Kiichiro, Kohno, Hideo, Tsuneoka, Hiroshi
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Molecular Vision 2012
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3538043/ https://www.ncbi.nlm.nih.gov/pubmed/23304068

Ejemplares similares

Photoreceptor degeneration in microphthalmia (Mitf) mice: partial rescue by pigment epithelium-derived factor
por: Chen, Yu, et al.
Publicado: (2019)

Expression pattern of Ccr2 and Cx3cr1 in inherited retinal degeneration
por: Kohno, Hideo, et al.
Publicado: (2015)

Degradation of Photoreceptor Outer Segments by the Retinal Pigment Epithelium Requires Pigment Epithelium-Derived Factor Receptor (PEDF-R)
por: Bullock, Jeanee, et al.
Publicado: (2021)

Foveal threshold and photoreceptor integrity for prediction of visual acuity after intravitreal aflibercept on age-related macular degeneration
por: Sakai, Tsutomu, et al.
Publicado: (2018)

The Retinal Pigment Epithelium: a Convenient Source of New Photoreceptor cells?
por: Wang, Shu-Zhen, et al.
Publicado: (2014)

Retinal Pigment Epithelium and Photoreceptor Preconditioning Protection Requires Docosanoid Signaling
por: Knott, Eric J., et al.
Publicado: (2017)

Treatment of experimental autoimmune uveoretinitis with peroxisome proliferator-activated receptor α agonist fenofibrate
por: Osada, Miho, et al.
Publicado: (2014)

A Case of Retinitis Pigmentosa Requiring Vitrectomy because of Repeated Vitreous Hemorrhage
por: Watanabe, Akira, et al.
Publicado: (2011)

Transplantation of retinal pigment epithelium and photoreceptors generated concomitantly via small molecule-mediated differentiation rescues visual function in rodent models of retinal degeneration
por: Surendran, Harshini, et al.
Publicado: (2021)

Presumed toxoplasmic central retinal artery occlusion and multifocal retinitis with perivascular sheathing
por: Arai, Haruka, et al.
Publicado: (2014)

Localization of Acetylcholine-Related Molecules in the Retina: Implication of the Communication from Photoreceptor to Retinal Pigment Epithelium
por: Matsumoto, Hidetaka, et al.
Publicado: (2012)

Retinal sensitivity and photoreceptor arrangement changes secondary to congenital simple hamartoma of retinal pigment epithelium
por: Rodrigues, M. W., et al.
Publicado: (2019)

Arap1 loss causes retinal pigment epithelium phagocytic dysfunction and subsequent photoreceptor death
por: Shao, Andy, et al.
Publicado: (2022)

Otx2-Genetically Modified Retinal Pigment Epithelial Cells Rescue Photoreceptors after Transplantation
por: Kole, Christo, et al.
Publicado: (2018)

Systemic immunotherapy delays photoreceptor cell loss and prevents vascular pathology in Royal College of Surgeons rats
por: Adamus, Grazyna, et al.
Publicado: (2012)

Circulating Reactive Oxidant Causes Apoptosis of Retinal Pigment Epithelium and Cone Photoreceptors in the Mouse Central Retina
por: Wang, Wei, et al.
Publicado: (2011)

Novel Localization of Peripherin 2, the Photoreceptor-Specific Retinal Degeneration Slow Protein, in Retinal Pigment Epithelium
por: Uhl, Patrizia B., et al.
Publicado: (2015)

Histochemical study of retinal photoreceptors development during pre- and postnatal period and their association with retinal pigment epithelium
por: Ebrahimi, Vahid, et al.
Publicado: (2014)

Pigment epithelium-derived factor hinders photoreceptor cell death by reducing intracellular calcium in the degenerating retina
por: Comitato, Antonella, et al.
Publicado: (2018)

Injury of photoreceptors and retinal pigment epithelium in macular area of a preterm infant: A case analysis
por: Sun, Xiantao, et al.
Publicado: (2020)

Inflammation of the retinal pigment epithelium drives early-onset photoreceptor degeneration in Mertk-associated retinitis pigmentosa
por: Mercau, Maria E., et al.
Publicado: (2023)

Ablation of pigment epithelium-derived factor receptor (PEDF-R/Pnpla2) causes photoreceptor degeneration
por: Bernardo-Colón, Alexandra, et al.
Publicado: (2023)

Co-grafts of Human Embryonic Stem Cell Derived Retina Organoids and Retinal Pigment Epithelium for Retinal Reconstruction in Immunodeficient Retinal Degenerate Royal College of Surgeons Rats
por: Thomas, Biju B., et al.
Publicado: (2021)

Taurine rescues mitochondria-related metabolic impairments in the patient-derived induced pluripotent stem cells and epithelial-mesenchymal transition in the retinal pigment epithelium
por: Homma, Kohei, et al.
Publicado: (2021)

Dorsal-Ventral Differences in Retinal Structure in the Pigmented Royal College of Surgeons Model of Retinal Degeneration
por: Greferath, Una, et al.
Publicado: (2021)

Differential Roles of CD36 and αvβ5 Integrin in Photoreceptor Phagocytosis by the Retinal Pigment Epithelium
por: Finnemann, Silvia C., et al.
Publicado: (2001)

Hyperactivation of retina by light in mice leads to photoreceptor cell death mediated by VEGF and retinal pigment epithelium permeability
por: Cachafeiro, M, et al.
Publicado: (2013)

Effect of aging and lifestyle on photoreceptors and retinal pigment epithelium: cross-sectional study in a healthy Danish population
por: Harris, Jacob, et al.
Publicado: (2017)

Mitochondrial oxidative stress in the retinal pigment epithelium (RPE) led to metabolic dysfunction in both the RPE and retinal photoreceptors
por: Brown, Emily E., et al.
Publicado: (2019)

MERTK-Dependent Ensheathment of Photoreceptor Outer Segments by Human Pluripotent Stem Cell-Derived Retinal Pigment Epithelium
por: Almedawar, Seba, et al.
Publicado: (2020)

A Human Retinal Pigment Epithelium-Based Screening Platform Reveals Inducers of Photoreceptor Outer Segments Phagocytosis
por: Schreiter, Sven, et al.
Publicado: (2020)

Photoreceptor and Retinal Pigment Epithelium Relationships in Eyes With Vitelliform Macular Dystrophy Revealed by Multimodal Adaptive Optics Imaging
por: Liu, Tao, et al.
Publicado: (2022)

Focal electroretinogram and microperimetry testing of photoreceptor‐retinal pigment epithelium function in intermediate age‐related macular degeneration
por: Messenio, Dario, et al.
Publicado: (2021)

SPACR Encoded by IMPG1 Is Essential for Photoreceptor Survival by Interplaying between the Interphotoreceptor Matrix and the Retinal Pigment Epithelium
por: Olivier, Guillaume, et al.
Publicado: (2022)

The Royal College of Surgeons
Publicado: (1899)

Royal College of Surgeons
Publicado: (1921)

Royal College of Surgeons
Publicado: (1857)

Royal College of Surgeons
Publicado: (1857)

Royal College of Surgeons
Publicado: (1857)

Royal College of Surgeons
Publicado: (1909)

Cannot write session to /tmp/vufind_sessions/sess_p3b207ohjn61r05992c7i4l06s