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Anti-folate combination therapies and their effect on the development of drug resistance in Plasmodium vivax
Can we predict the rise and spread of resistance to multi-drug therapy in a more predictable manner? We raise this question after analyzing over 500 Plasmodium vivax isolates collected from different, geographically isolated regions of China for sequence variation in and around the dhfr and dhps gen...
Autores principales: | Ding, Shuai, Ye, Run, Zhang, Dongmei, Sun, Xiaodong, Zhou, Hongning, McCutchan, Thomas F., Pan, Weiqing |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3538286/ https://www.ncbi.nlm.nih.gov/pubmed/23301149 http://dx.doi.org/10.1038/srep01008 |
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