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Transgenic Mice Overexpressing Renin Exhibit Glucose Intolerance and Diet-Genotype Interactions
Numerous animal and clinical investigations have pointed to a potential role of the renin-angiotensin system (RAS) in the development of insulin resistance and diabetes in conditions of expanded fat mass. However, the mechanisms underlying this association remain unclear. We used a transgenic mouse...
Autores principales: | Fletcher, Sarah J., Kalupahana, Nishan S., Soltani-Bejnood, Morvarid, Kim, Jung Han, Saxton, Arnold M., Wasserman, David H., De Taeye, Bart, Voy, Brynn H., Quignard-Boulange, Annie, Moustaid-Moussa, Naima |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3538348/ https://www.ncbi.nlm.nih.gov/pubmed/23308073 http://dx.doi.org/10.3389/fendo.2012.00166 |
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