Neurofibromatosis Type 2 Tumor Suppressor Protein, NF2, Induces Proteasome-Mediated Degradation of JC Virus T-Antigen in Human Glioblastoma

Neurofibromatosis type 2 protein (NF2) has been shown to act as tumor suppressor primarily through its functions as a cytoskeletal scaffold. However, NF2 can also be found in the nucleus, where its role is less clear. Previously, our group has identified JC virus (JCV) tumor antigen (T-antigen) as a...

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Detalles Bibliográficos
Autores principales: Beltrami, Sarah, Branchetti, Emanuela, Sariyer, Ilker K., Otte, Jessica, Weaver, Michael, Gordon, Jennifer
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3538535/
https://www.ncbi.nlm.nih.gov/pubmed/23308224
http://dx.doi.org/10.1371/journal.pone.0053447

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