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RING Finger Protein 11 Targets TBK1/IKKi Kinases to Inhibit Antiviral Signaling

A key feature of the innate antiviral immune response is a rapid nonspecific response to virus infection largely mediated by the induction and extracellular secretion of type I interferons (IFNs) that restrict virus replication. Cytoplasmic sensors such as RIG-I recognize viral RNA and trigger antiv...

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Detalles Bibliográficos
Autores principales: Charoenthongtrakul, Soratree, Gao, Linlin, Parvatiyar, Kislay, Lee, David, Harhaj, Edward W.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3538746/
https://www.ncbi.nlm.nih.gov/pubmed/23308279
http://dx.doi.org/10.1371/journal.pone.0053717