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RING Finger Protein 11 Targets TBK1/IKKi Kinases to Inhibit Antiviral Signaling
A key feature of the innate antiviral immune response is a rapid nonspecific response to virus infection largely mediated by the induction and extracellular secretion of type I interferons (IFNs) that restrict virus replication. Cytoplasmic sensors such as RIG-I recognize viral RNA and trigger antiv...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3538746/ https://www.ncbi.nlm.nih.gov/pubmed/23308279 http://dx.doi.org/10.1371/journal.pone.0053717 |