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Scattering of MCF7 Cells by Heregulin ß-1 Depends on the MEK and p38 MAP Kinase Pathway

Heregulin (HRG) β1 signaling promotes scattering of MCF7 cells by inducing breakdown of adherens and tight junctions. Here, we show that stimulation with HRG-β1 causes the F-actin backbone of junctions to destabilize prior to the loss of adherent proteins and scattering of the cells. The adherent pr...

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Detalles Bibliográficos
Autores principales:	Okoshi, Rintaro, Shu, Chung-Li, Ihara, Sayoko, Fukui, Yasuhisa
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2013
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3538754/ https://www.ncbi.nlm.nih.gov/pubmed/23308187 http://dx.doi.org/10.1371/journal.pone.0053298

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