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LCMV Glycosylation Modulates Viral Fitness and Cell Tropism
The glycoprotein (GP) of arenaviruses is glycosylated at 11 conserved N-glycosylation sites. We constructed recombinant lymphocytic choriomeningitis virus (rLCMV) featuring either additions or deletions of these N-glycans to investigate their role in the viral life cycle. N-glycosylation at two site...
Autores principales: | Bonhomme, Cyrille J., Knopp, Kristeene A., Bederka, Lydia H., Angelini, Megan M., Buchmeier, Michael J. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2013
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3538765/ https://www.ncbi.nlm.nih.gov/pubmed/23308183 http://dx.doi.org/10.1371/journal.pone.0053273 |
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