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Dual Function of Novel Pollen Coat (Surface) Proteins: IgE-binding Capacity and Proteolytic Activity Disrupting the Airway Epithelial Barrier

BACKGROUND: The pollen coat is the first structure of the pollen to encounter the mucosal immune system upon inhalation. Prior characterizations of pollen allergens have focused on water-soluble, cytoplasmic proteins, but have overlooked much of the extracellular pollen coat. Due to washing with org...

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Detalles Bibliográficos
Autores principales: Bashir, Mohamed Elfatih H., Ward, Jason M., Cummings, Matthew, Karrar, Eltayeb E., Root, Michael, Mohamed, Abu Bekr A., Naclerio, Robert M., Preuss, Daphne
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3538775/
https://www.ncbi.nlm.nih.gov/pubmed/23308195
http://dx.doi.org/10.1371/journal.pone.0053337