Cargando…
The secreted protein acidic and rich in cysteine (SPARC) induces endoplasmic reticulum stress leading to autophagy-mediated apoptosis in neuroblastoma
Our previous studies showed that overexpression of secreted protein acidic and rich in cysteine (SPARC) induced autophagy-mediated apoptosis in PNET cells. In the present study, we attempted to elucidate the molecular mechanisms and signaling cascades associated with SPARC overexpression in combinat...
Autores principales: | SAILAJA, G.S., BHOOPATHI, PRAVEEN, GORANTLA, BHARATHI, CHETTY, CHANDRAMU, GOGINENI, VENKATESWARA RAO, VELPULA, KIRAN KUMAR, GONDI, CHRISTOPHER S., RAO, JASTI S. |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
D.A. Spandidos
2012
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3538858/ https://www.ncbi.nlm.nih.gov/pubmed/23123816 http://dx.doi.org/10.3892/ijo.2012.1678 |
Ejemplares similares
-
SPARC Overexpression Inhibits Cell Proliferation in Neuroblastoma and Is Partly Mediated by Tumor Suppressor Protein PTEN and AKT
por: Bhoopathi, Praveen, et al.
Publicado: (2012) -
Epigenetic Regulation of miRNA-211 by MMP-9 Governs Glioma Cell Apoptosis, Chemosensitivity and Radiosensitivity
por: Asuthkar, Swapna, et al.
Publicado: (2012) -
MMP-2 mediates mesenchymal stem cell tropism towards medulloblastoma tumors
por: Bhoopathi, Praveen, et al.
Publicado: (2011) -
Suppression of MMP-2 Attenuates TNF-α Induced NF-κB Activation and Leads to JNK Mediated Cell Death in Glioma
por: Kesanakurti, Divya, et al.
Publicado: (2011) -
Oncogenic role of p53 is suppressed by si-RNA bicistronic construct of uPA, uPAR and cathepsin-B in meningiomas both in vitro and in vivo
por: Gupta, Reshu, et al.
Publicado: (2021)