Melanocyte Colonization and Pigmentation of Breast Carcinoma: Pathological and Clinical Aspects

Introduction. Melanocyte colonization of breast carcinoma by nonneoplastic melanocytes of epidermal origin is a rare and serious condition first described in 1977. We report on the exceptional clinical and pathological features of this migration phenomenon in a 74-year-old patient. Discussion. The p...

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Autores principales: Mele, Marco, Laurberg, Tinne, Engberg Damsgaard, Tine, Funder, Jonas, Jensen, Vibeke
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2012
Materias:
Case Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3539375/
https://www.ncbi.nlm.nih.gov/pubmed/23320234
http://dx.doi.org/10.1155/2012/427628
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author Mele, Marco
Laurberg, Tinne
Engberg Damsgaard, Tine
Funder, Jonas
Jensen, Vibeke
author_facet Mele, Marco
Laurberg, Tinne
Engberg Damsgaard, Tine
Funder, Jonas
Jensen, Vibeke
author_sort Mele, Marco
collection PubMed
description Introduction. Melanocyte colonization of breast carcinoma by nonneoplastic melanocytes of epidermal origin is a rare and serious condition first described in 1977. We report on the exceptional clinical and pathological features of this migration phenomenon in a 74-year-old patient. Discussion. The pathogenesis by which melanocyte migration takes place is not known, but a breached basement membrane is considered essential. Conclusion. Histological examination and additional staining of skin are essential to differentiate breast cancer melanosis from malignant melanoma.
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spelling pubmed-35393752013-01-14 Melanocyte Colonization and Pigmentation of Breast Carcinoma: Pathological and Clinical Aspects Mele, Marco Laurberg, Tinne Engberg Damsgaard, Tine Funder, Jonas Jensen, Vibeke Case Rep Pathol Case Report Introduction. Melanocyte colonization of breast carcinoma by nonneoplastic melanocytes of epidermal origin is a rare and serious condition first described in 1977. We report on the exceptional clinical and pathological features of this migration phenomenon in a 74-year-old patient. Discussion. The pathogenesis by which melanocyte migration takes place is not known, but a breached basement membrane is considered essential. Conclusion. Histological examination and additional staining of skin are essential to differentiate breast cancer melanosis from malignant melanoma. Hindawi Publishing Corporation 2012 2012-12-20 /pmc/articles/PMC3539375/ /pubmed/23320234 http://dx.doi.org/10.1155/2012/427628 Text en Copyright © 2012 Marco Mele et al. https://creativecommons.org/licenses/by/3.0/ This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Case Report
Mele, Marco
Laurberg, Tinne
Engberg Damsgaard, Tine
Funder, Jonas
Jensen, Vibeke
Melanocyte Colonization and Pigmentation of Breast Carcinoma: Pathological and Clinical Aspects
title Melanocyte Colonization and Pigmentation of Breast Carcinoma: Pathological and Clinical Aspects
title_full Melanocyte Colonization and Pigmentation of Breast Carcinoma: Pathological and Clinical Aspects
title_fullStr Melanocyte Colonization and Pigmentation of Breast Carcinoma: Pathological and Clinical Aspects
title_full_unstemmed Melanocyte Colonization and Pigmentation of Breast Carcinoma: Pathological and Clinical Aspects
title_short Melanocyte Colonization and Pigmentation of Breast Carcinoma: Pathological and Clinical Aspects
title_sort melanocyte colonization and pigmentation of breast carcinoma: pathological and clinical aspects
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3539375/
https://www.ncbi.nlm.nih.gov/pubmed/23320234
http://dx.doi.org/10.1155/2012/427628
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