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Solution Structures of PPARγ2/RXRα Complexes

PPARγ is a key regulator of glucose homeostasis and insulin sensitization. PPARγ must heterodimerize with its dimeric partner, the retinoid X receptor (RXR), to bind DNA and associated coactivators such as p160 family members or PGC-1α to regulate gene networks. To understand how coactivators are re...

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Detalles Bibliográficos
Autores principales:	Osz, Judit, Pethoukhov, Maxim V., Sirigu, Serena, Svergun, Dmitri I., Moras, Dino, Rochel, Natacha
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Hindawi Publishing Corporation 2012
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3539437/ https://www.ncbi.nlm.nih.gov/pubmed/23319938 http://dx.doi.org/10.1155/2012/701412

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