Regulation of the instantaneous inward rectifier and the delayed outward rectifier potassium channels by Captopril and Angiotensin II via the Phosphoinositide-3 kinase pathway in volume-overload-induced hypertrophied cardiac myocytes

BACKGROUND: Early development of cardiac hypertrophy may be beneficial but sustained hypertrophic activation leads to myocardial dysfunction. Regulation of the repolarizing currents can be modulated by the activation of humoral factors, such as angiotensin II (ANG II) through protein kinases. The ai...

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Detalles Bibliográficos
Autores principales: Alvin, Zikiar, Laurence, Graham G., Coleman, Bernell R., Zhao, Aiqiu, Hajj-Moussa, Majd, Haddad, Georges E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: International Scientific Literature, Inc. 2011
Materias:
Basic Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3539556/
https://www.ncbi.nlm.nih.gov/pubmed/21709626
http://dx.doi.org/10.12659/MSM.881843

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