Cargando…

Correlation of Peroxisome Proliferator-Activated Receptor-γ (PPAR-γ) and Retinoid X Receptor-α (RXR-α) expression with clinical risk factors in patients with advanced carotid atherosclerosis

BACKGROUND: Peroxisome proliferator-activated Receptor-γ (PPAR-γ) and its nuclear partners, the Retinoid X Receptors (RXRs), have been recognized as crucial players in the pathogenesis of atherosclerosis. The present study aimed to assess the clinical significance of PPAR-γ and RXR-α expression in d...

Descripción completa

Detalles Bibliográficos
Autores principales:	Giaginis, Constantinos, Klonaris, Christos, Katsargyris, Athanasios, Kouraklis, Gregorios, Spiliopoulou, Chara, Theocharis, Stamatios
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	International Scientific Literature, Inc. 2011
Materias:	Clinical Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3539575/ https://www.ncbi.nlm.nih.gov/pubmed/21709632 http://dx.doi.org/10.12659/MSM.881849

Ejemplares similares

Correlation of plasma osteoprotegerin (OPG) and receptor activator of the nuclear factor κB ligand (RANKL) levels with clinical risk factors in patients with advanced carotid atherosclerosis
por: Giaginis, Constantinos, et al.
Publicado: (2012)

Allosteric Pathways in the PPARγ-RXRα nuclear receptor complex
por: Ricci, Clarisse G., et al.
Publicado: (2016)

Heterodimer formation with retinoic acid receptor RXRα modulates coactivator recruitment by peroxisome proliferator-activated receptor PPARγ
por: Kilu, Whitney, et al.
Publicado: (2021)

Attenuation of Colon Inflammation through Activators of the Retinoid X Receptor (Rxr)/Peroxisome Proliferator–Activated Receptor γ (Pparγ) Heterodimer: A Basis for New Therapeutic Strategies
por: Desreumaux, Pierre, et al.
Publicado: (2001)

Microsecond MD Simulations to Explore the Structural and Energetic Differences between the Human RXRα-PPARγ vs. RXRα-PPARγ-DNA
por: Azam, Faizul, et al.
Publicado: (2022)

Phosphorylation of PPARγ Affects the Collective Motions of the PPARγ-RXRα-DNA Complex
por: Lemkul, Justin A., et al.
Publicado: (2015)

Solution Structures of PPARγ2/RXRα Complexes
por: Osz, Judit, et al.
Publicado: (2012)

Peroxisome Proliferator-Activated Receptor-γ Ligands: Potential Pharmacological Agents for Targeting the Angiogenesis Signaling Cascade in Cancer
por: Giaginis, Costas, et al.
Publicado: (2008)

Molecular Determinants of Magnolol Targeting Both RXRα and PPARγ
por: Zhang, Haitao, et al.
Publicado: (2011)

Evasion of immunosurveillance by genomic alterations of PPARγ/RXRα in bladder cancer
por: Korpal, Manav, et al.
Publicado: (2017)

A retinoid X receptor (RXR)-selective retinoid reveals that RXR-α is potentially a therapeutic target in breast cancer cell lines, and that it potentiates antiproliferative and apoptotic responses to peroxisome proliferator-activated receptor ligands
por: Crowe, David L, et al.
Publicado: (2004)

PPARγ phase separates with RXRα at PPREs to regulate target gene expression
por: Li, Zhean, et al.
Publicado: (2022)

Phytochemicals Mediate the Expression and Activity of OCTN2 as Activators of the PPARγ/RXRα Pathway
por: Luo, Jian, et al.
Publicado: (2016)

Dibutyltin Compounds Effects on PPARγ/RXRα Activity, Adipogenesis, and Inflammation in Mammalians Cells
por: Milton, Flora A., et al.
Publicado: (2017)

Author Correction: Evasion of immunosurveillance by genomic alterations of PPARγ/RXRα in bladder cancer
por: Korpal, Manav, et al.
Publicado: (2019)

Cytoplasmic Colocalization of RXRα and PPARγ as an Independent Negative Prognosticator for Breast Cancer Patients
por: Shao, Wanting, et al.
Publicado: (2022)

Different skeletal effects of the peroxisome proliferator activated receptor (PPAR)α agonist fenofibrate and the PPARγ agonist pioglitazone
por: Syversen, Unni, et al.
Publicado: (2009)

T-Cell Death-Associated Gene 51 Is a Novel Negative Regulator of PPARγ That Inhibits PPARγ-RXRα Heterodimer Formation in Adipogenesis
por: Kim, Sumi, et al.
Publicado: (2021)

Heat Shock Protein-27, -60 and -90 expression in gastric cancer: association with clinicopathological variables and patient survival
por: Giaginis, Constantinos, et al.
Publicado: (2009)

RXRα is Upregulated in First Trimester Endometrial Glands of Spontaneous Abortions Unlike LXR and PPARγ
por: Knabl, J., et al.
Publicado: (2016)

Underexpression of peroxisome proliferator-activated receptor (PPAR)γ in PAX8/PPARγ-negative thyroid tumours
por: Marques, A R, et al.
Publicado: (2004)

Expression of peroxisome proliferator-activated receptor (PPAR)γ in gastric cancer and inhibitory effects of PPARγ agonists
por: Sato, H, et al.
Publicado: (2000)

PPARα-mediated peroxisome induction compensates PPARγ-deficiency in bronchiolar club cells
por: Karnati, Srikanth, et al.
Publicado: (2018)

Effects of peroxisome proliferator activated receptors (PPAR)-γ and -α agonists on cochlear protection from oxidative stress
por: Sekulic-Jablanovic, Marijana, et al.
Publicado: (2017)

Peroxisome Proliferator Activator Receptor (PPAR)-γ Ligand, but Not PPAR-α, Ameliorates Cyclophosphamide-Induced Oxidative Stress and Inflammation in Rat Liver
por: El-Sheikh, Azza A. K., et al.
Publicado: (2014)

Peroxisome proliferator-activated receptors (PPARα, PPARγ and PPARβ/δ) gene expression profile on ram spermatozoa and their relation to the sperm motility
por: Kadivar, Ali, et al.
Publicado: (2016)

Interleukin-17 promotes proliferation, migration, and invasion of trophoblasts via regulating PPAR-γ/RXR-α/Wnt signaling
por: Zhang, Zhuo, et al.
Publicado: (2022)

Scaffold-Based Pan-Agonist Design for the PPARα, PPARβ and PPARγ Receptors
por: Zhang, Li-Song, et al.
Publicado: (2012)

Histone deacetylase (HDAC)-1, −2, −4 and −6 expression in human pancreatic adenocarcinoma: associations with clinicopathological parameters, tumor proliferative capacity and patients’ survival
por: Giaginis, Constantinos, et al.
Publicado: (2015)

Oleamide activates peroxisome proliferator-activated receptor gamma (PPARγ) in vitro
por: Alexander, Stephen PH, et al.
Publicado: (2012)

Functions of Peroxisome Proliferator-Activated Receptor Gamma (PPARγ) in Gynecologic Disorders
por: Ren, Ping, et al.
Publicado: (2015)

A noncanonical PPARγ/RXRα-binding sequence regulates leptin expression in response to changes in adipose tissue mass
por: Zhang, Yinxin, et al.
Publicado: (2018)

RXRα Positively Regulates Expression of the Chicken PLIN1 Gene in a PPARγ-Independent Manner and Promotes Adipogenesis
por: Sun, Yuhang, et al.
Publicado: (2020)

PML-RARα interaction with TRIB3 impedes PPARγ/RXR function and triggers dyslipidemia in acute promyelocytic leukemia
por: Li, Ke, et al.
Publicado: (2020)

New Target Genes for the Peroxisome Proliferator-Activated Receptor-γ (PPARγ) Antitumour Activity: Perspectives from the Insulin Receptor
por: Foti, Daniela P., et al.
Publicado: (2009)

A Novel Splicing Variant of Peroxisome Proliferator-Activated Receptor-γ (Pparγ1sv) Cooperatively Regulates Adipocyte Differentiation with Pparγ2
por: Takenaka, Yasuhiro, et al.
Publicado: (2013)

In Silico Identification and Experimental Validation of (−)-Muqubilin A, a Marine Norterpene Peroxide, as PPARα/γ-RXRα Agonist and RARα Positive Allosteric Modulator
por: D’Aniello, Enrico, et al.
Publicado: (2019)

Synergistic Effects of PPARγ Ligands and Retinoids in Cancer Treatment
por: Shimizu, Masahito, et al.
Publicado: (2008)

PPARα/γ-Independent Effects of PPARα/γ Ligands on Cysteinyl Leukotriene Production in Mast Cells
por: Yamashita, Masamichi
Publicado: (2008)

Omega 3 polyunsaturated fatty acid improves spatial learning and hippocampal Peroxisome Proliferator Activated Receptors (PPARα and PPARγ) gene expression in rats
por: Hajjar, Toktam, et al.
Publicado: (2012)

Cannot write session to /tmp/vufind_sessions/sess_b8hq41ahsefgcav0t34qhimthf