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Cerebrospinal Fluid PKR Level Predicts Cognitive Decline in Alzheimer’s Disease

The cerebrospinal fluid (CSF) levels of the proapoptotic kinase R (PKR) and its phosphorylated PKR (pPKR) are increased in Alzheimer’s disease (AD), but whether CSF PKR concentrations are associated with cognitive decline in AD patients remain unknown. In this study, 41 consecutive patients with AD...

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Detalles Bibliográficos
Autores principales: Dumurgier, Julien, Mouton-Liger, Francois, Lapalus, Pauline, Prevot, Magali, Laplanche, Jean-Louis, Hugon, Jacques, Paquet, Claire
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3539966/
https://www.ncbi.nlm.nih.gov/pubmed/23320095
http://dx.doi.org/10.1371/journal.pone.0053587