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A Critical HA1 Neutralizing Domain of H5N1 Influenza in an Optimal Conformation Induces Strong Cross-Protection
The highly pathogenic avian influenza (HPAI) H5N1 viruses, especially the laboratory-generated H5N1 mutants, have demonstrated the potential to cross the species barrier and infect mammals and humans. Consequently, the design of an effective and safe anti-H5N1 vaccine is essential. We previously dem...
Autores principales: | Du, Lanying, Zhao, Guangyu, Sun, Shihui, Zhang, Xiujuan, Zhou, Xiaojun, Guo, Yan, Li, Ye, Zhou, Yusen, Jiang, Shibo |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3539987/ https://www.ncbi.nlm.nih.gov/pubmed/23320093 http://dx.doi.org/10.1371/journal.pone.0053568 |
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