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Protease activated receptor 1-induced glutamate release in cultured astrocytes is mediated by Bestrophin-1 channel but not by vesicular exocytosis
BACKGROUND: Glutamate is the major transmitter that mediates the principal form of excitatory synaptic transmission in the brain. It has been well established that glutamate is released via Ca(2+)-dependent exocytosis of glutamate-containing vesicles in neurons. However, whether astrocytes exocytose...
Autores principales: | Oh, Soo-Jin, Han, Kyung-Seok, Park, Hyungju, Woo, Dong ho, Kim, Hye Yun, Traynelis, Stephen F, Lee, C Justin |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3539998/ https://www.ncbi.nlm.nih.gov/pubmed/23062602 http://dx.doi.org/10.1186/1756-6606-5-38 |
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