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Activation of the Cellular Unfolded Protein Response by Recombinant Adeno-Associated Virus Vectors

The unfolded protein response (UPR) is a stress-induced cyto-protective mechanism elicited towards an influx of large amount of proteins in the endoplasmic reticulum (ER). In the present study, we evaluated if AAV manipulates the UPR pathways during its infection. We first examined the role of the t...

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Detalles Bibliográficos
Autores principales:	Balakrishnan, Balaji, Sen, Dwaipayan, Hareendran, Sangeetha, Roshini, Vaani, David, Sachin, Srivastava, Alok, Jayandharan, Giridhara R.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2013
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3540029/ https://www.ncbi.nlm.nih.gov/pubmed/23320106 http://dx.doi.org/10.1371/journal.pone.0053845

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