Comprehensive Analysis and Identification of the Human STIM1 Domains for Structural and Functional Studies

STIM1 is a Ca(2+) sensor within the ER membrane known to activate the plasma membrane store-operated Ca(2+) channel upon depletion of its target ion in the ER lumen. This activation is a crucial step to initiate the Ca(2+) signaling cascades within various cell types. Human STIM1 is a 77.4 kDa prote...

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Detalles Bibliográficos
Autores principales: How, Jonathan, Zhang, Ai, Phillips, Margaret, Reynaud, Aline, Lu, Si Yan, Pan, Lucy Xin, Ho, Hai Ting, Yau, Yin Hoe, Guskov, Albert, Pervushin, Konstantin, Shochat, Susana Geifman, Eshaghi, Said
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3540032/
https://www.ncbi.nlm.nih.gov/pubmed/23320111
http://dx.doi.org/10.1371/journal.pone.0053979

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