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Dynamic Increase in Extracellular ATP Accelerates Photoreceptor Cell Apoptosis via Ligation of P2RX7 in Subretinal Hemorrhage
Photoreceptor degeneration is the most critical cause of visual impairment in age-related macular degeneration (AMD). In neovascular form of AMD, severe photoreceptor loss develops with subretinal hemorrhage due to choroidal neovascularization (CNV), growth of abnormal blood vessels from choroidal c...
Autores principales: | Notomi, Shoji, Hisatomi, Toshio, Murakami, Yusuke, Terasaki, Hiroto, Sonoda, Shozo, Asato, Ryo, Takeda, Atsunobu, Ikeda, Yasuhiro, Enaida, Hiroshi, Sakamoto, Taiji, Ishibashi, Tatsuro |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3540091/ https://www.ncbi.nlm.nih.gov/pubmed/23308196 http://dx.doi.org/10.1371/journal.pone.0053338 |
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