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Endothelial Apelin-FGF Link Mediated by MicroRNAs 424 and 503 is Disrupted in Pulmonary Arterial Hypertension

Pulmonary arterial hypertension is characterized by vascular remodeling associated with obliteration of pulmonary arterioles and formation of plexiform lesions comprised of hyperproliferative endothelial and vascular smooth muscle cells. Here, we describe a novel, microRNA-dependent association betw...

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Detalles Bibliográficos
Autores principales: Kim, Jongmin, Kang, Yujung, Kojima, Yoko, Lighthouse, Janet K., Hu, Xiaoyue, Aldred, Micheala A., McLean, Danielle L., Park, Hyekyung, Comhair, Suzy A., Greif, Daniel M., Erzurum, Serpil C., Chun, Hyung J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3540168/
https://www.ncbi.nlm.nih.gov/pubmed/23263626
http://dx.doi.org/10.1038/nm.3040