Phospholipase Cζ rescues failed oocyte activation in a prototype of male factor infertility

OBJECTIVE: To determine the effect of infertility-linked sperm phospholipase Cζ (PLCζ) mutations on their ability to trigger oocyte Ca(2+) oscillations and development, and also to evaluate the potential therapeutic utility of wild-type, recombinant PLCζ protein for rescuing failed oocyte activation...

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Detalles Bibliográficos
Autores principales: Nomikos, Michail, Yu, Yuansong, Elgmati, Khalil, Theodoridou, Maria, Campbell, Karen, Vassilakopoulou, Vyronia, Zikos, Christos, Livaniou, Evangelia, Amso, Nazar, Nounesis, George, Swann, Karl, Lai, F. Anthony
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier for the American Society for Reproductive Medicine 2013
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3540263/
https://www.ncbi.nlm.nih.gov/pubmed/22999959
http://dx.doi.org/10.1016/j.fertnstert.2012.08.035

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3540263/
https://www.ncbi.nlm.nih.gov/pubmed/22999959
http://dx.doi.org/10.1016/j.fertnstert.2012.08.035

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