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Purinergic signalling in the rostral ventro-lateral medulla controls sympathetic drive and contributes to the progression of heart failure following myocardial infarction in rats

Heart failure may lead to hypoperfusion and hypooxygenation of tissues and this is often exacerbated by central and obstructive sleep apnoeas associated with recurrent episodes of systemic hypoxia which triggers release of ATP within the CNS circuits controlling sympathetic outflow. Using in vitro a...

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Detalles Bibliográficos
Autores principales: Marina, Nephtali, Tang, Feige, Figueiredo, Melina, Mastitskaya, Svetlana, Kasimov, Vitaliy, Mohamed-Ali, Vidya, Roloff, Eva, Teschemacher, Anja G., Gourine, Alexander V., Kasparov, Sergey
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer-Verlag 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3540348/
https://www.ncbi.nlm.nih.gov/pubmed/23187902
http://dx.doi.org/10.1007/s00395-012-0317-x

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