Feasibility, safety and pharmacokinetic study of hepatic administration of drug-eluting beads loaded with irinotecan (DEBIRI) followed by intravenous administration of irinotecan in a porcine model

Irinotecan eluting embolization beads (DEBIRI) are currently being evaluated in the clinic for the treatment of colorectal cancer metastases to the liver. The aim of this study was to determine the safety and pharmacokinetics associated with two cycles of hepatic embolization using DEBIRI followed b...

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Detalles Bibliográficos
Autores principales: Lewis, Andrew L., Holden, Rachel R., Chung, S. Ting, Czuczman, Peter, Kuchel, Timothy, Finnie, John, Porter, Susan, Foster, David
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer US 2012
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3540360/
https://www.ncbi.nlm.nih.gov/pubmed/23015264
http://dx.doi.org/10.1007/s10856-012-4768-2

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