Mixed Germ Cell Tumor with Extensive Yolk Sac Tumor Elements in the Frontal Lobe of an Adult

Intracranial nongerminomatous germ cell tumors (NGGCTs) in unusual locations are extremely rare. Here, we report a case of a yolk sac tumor in the frontal lobe in a middle-aged patient. A 42-year-old man was admitted to our hospital for headache and nausea. Magnetic resonance imaging (MRI) showed an...

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Autores principales: Takahashi, Toshihide, Ishikawa, Eiichi, Masuda, Yosuke, Yamamoto, Tetsuya, Sato, Taiki, Shibuya, Makoto, Matsumura, Akira
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2012
Materias:
Case Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3540654/
https://www.ncbi.nlm.nih.gov/pubmed/23326746
http://dx.doi.org/10.1155/2012/473790
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author Takahashi, Toshihide
Ishikawa, Eiichi
Masuda, Yosuke
Yamamoto, Tetsuya
Sato, Taiki
Shibuya, Makoto
Matsumura, Akira
author_facet Takahashi, Toshihide
Ishikawa, Eiichi
Masuda, Yosuke
Yamamoto, Tetsuya
Sato, Taiki
Shibuya, Makoto
Matsumura, Akira
author_sort Takahashi, Toshihide
collection PubMed
description Intracranial nongerminomatous germ cell tumors (NGGCTs) in unusual locations are extremely rare. Here, we report a case of a yolk sac tumor in the frontal lobe in a middle-aged patient. A 42-year-old man was admitted to our hospital for headache and nausea. Magnetic resonance imaging (MRI) showed an enhanced mass lesion with a marked cyst component. The serum alpha-fetoprotein (αFP) level was extremely high. Histological examination of specimens after subtotal removal revealed a primary mixed germ cell tumor with extensive yolk sac tumor elements, often referred to as an intracranial “yolk sac tumor.” The preoperative diagnosis of NGGCTs in unusual age and locations is extremely difficult. Clinicians should consider the possibility of NGGCTs, including yolk sac tumors, when intracranial tumors with unusual MRI findings are encountered.
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spelling pubmed-35406542013-01-16 Mixed Germ Cell Tumor with Extensive Yolk Sac Tumor Elements in the Frontal Lobe of an Adult Takahashi, Toshihide Ishikawa, Eiichi Masuda, Yosuke Yamamoto, Tetsuya Sato, Taiki Shibuya, Makoto Matsumura, Akira Case Rep Surg Case Report Intracranial nongerminomatous germ cell tumors (NGGCTs) in unusual locations are extremely rare. Here, we report a case of a yolk sac tumor in the frontal lobe in a middle-aged patient. A 42-year-old man was admitted to our hospital for headache and nausea. Magnetic resonance imaging (MRI) showed an enhanced mass lesion with a marked cyst component. The serum alpha-fetoprotein (αFP) level was extremely high. Histological examination of specimens after subtotal removal revealed a primary mixed germ cell tumor with extensive yolk sac tumor elements, often referred to as an intracranial “yolk sac tumor.” The preoperative diagnosis of NGGCTs in unusual age and locations is extremely difficult. Clinicians should consider the possibility of NGGCTs, including yolk sac tumors, when intracranial tumors with unusual MRI findings are encountered. Hindawi Publishing Corporation 2012 2012-12-24 /pmc/articles/PMC3540654/ /pubmed/23326746 http://dx.doi.org/10.1155/2012/473790 Text en Copyright © 2012 Toshihide Takahashi et al. https://creativecommons.org/licenses/by/3.0/ This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Case Report
Takahashi, Toshihide
Ishikawa, Eiichi
Masuda, Yosuke
Yamamoto, Tetsuya
Sato, Taiki
Shibuya, Makoto
Matsumura, Akira
Mixed Germ Cell Tumor with Extensive Yolk Sac Tumor Elements in the Frontal Lobe of an Adult
title Mixed Germ Cell Tumor with Extensive Yolk Sac Tumor Elements in the Frontal Lobe of an Adult
title_full Mixed Germ Cell Tumor with Extensive Yolk Sac Tumor Elements in the Frontal Lobe of an Adult
title_fullStr Mixed Germ Cell Tumor with Extensive Yolk Sac Tumor Elements in the Frontal Lobe of an Adult
title_full_unstemmed Mixed Germ Cell Tumor with Extensive Yolk Sac Tumor Elements in the Frontal Lobe of an Adult
title_short Mixed Germ Cell Tumor with Extensive Yolk Sac Tumor Elements in the Frontal Lobe of an Adult
title_sort mixed germ cell tumor with extensive yolk sac tumor elements in the frontal lobe of an adult
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3540654/
https://www.ncbi.nlm.nih.gov/pubmed/23326746
http://dx.doi.org/10.1155/2012/473790
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