Bone Morphogenetic Protein‐2 Decreases MicroRNA‐30b and MicroRNA‐30c to Promote Vascular Smooth Muscle Cell Calcification

BACKGROUND: Vascular calcification resembles bone formation and involves vascular smooth muscle cell (SMC) transition to an osteoblast‐like phenotype to express Runx2, a master osteoblast transcription factor. One possible mechanism by which Runx2 protein expression is induced is downregulation of i...

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Detalles Bibliográficos
Autores principales: Balderman, Joshua A. F., Lee, Hae‐Young, Mahoney, Christopher E., Handy, Diane E., White, Kevin, Annis, Sofia, Lebeche, Djamel, Hajjar, Roger J., Loscalzo, Joseph, Leopold, Jane A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Blackwell Publishing Ltd 2012
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3540659/
https://www.ncbi.nlm.nih.gov/pubmed/23316327
http://dx.doi.org/10.1161/JAHA.112.003905

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