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Type 2 Diabetes Restricts Multipotency of Mesenchymal Stem Cells and Impairs Their Capacity to Augment Postischemic Neovascularization in db/db Mice

BACKGROUND: This study tested the hypothesis that type 2 diabetes restricts multipotency of db/db mesenchymal stem cells (MSCs), promotes their terminal differentiation into adipocytes rather than endothelial cells, thereby promotes adipocytic infiltration into ischemic muscles, and reduces their ca...

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Detalles Bibliográficos
Autores principales:	Yan, Jinglian, Tie, Guodong, Wang, Shouying, Messina, Katharine E., DiDato, Sebastian, Guo, Sujuan, Messina, Louis M.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Blackwell Publishing Ltd 2012
Materias:	Original Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3540677/ https://www.ncbi.nlm.nih.gov/pubmed/23316315 http://dx.doi.org/10.1161/JAHA.112.002238

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