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In Vivo Cardiac Cellular Reprogramming Efficacy Is Enhanced by Angiogenic Preconditioning of the Infarcted Myocardium With Vascular Endothelial Growth Factor

BACKGROUND: In situ cellular reprogramming offers the possibility of regenerating functional cardiomyocytes directly from scar fibroblasts, obviating the challenges of cell implantation. We hypothesized that pretreating scar with gene transfer of the angiogenic vascular endothelial growth factor (VE...

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Detalles Bibliográficos
Autores principales: Mathison, Megumi, P. Gersch, Robert, Nasser, Ahmed, Lilo, Sarit, Korman, Mallory, Fourman, Mitchell, Hackett, Neil, Shroyer, Kenneth, Yang, Jianchang, Ma, Yupo, Crystal, Ronald G., Rosengart, Todd K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Blackwell Publishing Ltd 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3540681/
https://www.ncbi.nlm.nih.gov/pubmed/23316332
http://dx.doi.org/10.1161/JAHA.112.005652

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