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Hepatic Angiomyolipoma: Diagnostic Findings and Management

Angiomyolipoma (AML) is a benign mesenchymal tumor that is frequently found in the kidney and, rarely, in the liver. The natural history of hepatic AML has not been clarified, and, because of the similar patterns in imaging studies, such as ultrasonography, computed tomography, and magnetic resonanc...

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Detalles Bibliográficos
Autores principales: Kamimura, Kenya, Nomoto, Minoru, Aoyagi, Yutaka
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3540709/
https://www.ncbi.nlm.nih.gov/pubmed/23320180
http://dx.doi.org/10.1155/2012/410781
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author Kamimura, Kenya
Nomoto, Minoru
Aoyagi, Yutaka
author_facet Kamimura, Kenya
Nomoto, Minoru
Aoyagi, Yutaka
author_sort Kamimura, Kenya
collection PubMed
description Angiomyolipoma (AML) is a benign mesenchymal tumor that is frequently found in the kidney and, rarely, in the liver. The natural history of hepatic AML has not been clarified, and, because of the similar patterns in imaging studies, such as ultrasonography, computed tomography, and magnetic resonance imaging, some of these tumors have been overdiagnosed as hepatocellular carcinoma in the past. With an increase in the number of case reports showing detailed imaging studies and immunohistochemical staining of the tumor with human melanoma black-45, the diagnostic accuracy is also increasing. In this paper, we focused on the role of noninvasive imaging studies and histological diagnosis showing distinctive characteristics of this tumor. In addition, because several reports have described tumor progression in terms of size, recurrence after surgical resection, metastasis to other organs, and portal thrombosis, we summarized these cases for the management and discussed the indications for the surgical treatment of this tumor.
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spelling pubmed-35407092013-01-14 Hepatic Angiomyolipoma: Diagnostic Findings and Management Kamimura, Kenya Nomoto, Minoru Aoyagi, Yutaka Int J Hepatol Review Article Angiomyolipoma (AML) is a benign mesenchymal tumor that is frequently found in the kidney and, rarely, in the liver. The natural history of hepatic AML has not been clarified, and, because of the similar patterns in imaging studies, such as ultrasonography, computed tomography, and magnetic resonance imaging, some of these tumors have been overdiagnosed as hepatocellular carcinoma in the past. With an increase in the number of case reports showing detailed imaging studies and immunohistochemical staining of the tumor with human melanoma black-45, the diagnostic accuracy is also increasing. In this paper, we focused on the role of noninvasive imaging studies and histological diagnosis showing distinctive characteristics of this tumor. In addition, because several reports have described tumor progression in terms of size, recurrence after surgical resection, metastasis to other organs, and portal thrombosis, we summarized these cases for the management and discussed the indications for the surgical treatment of this tumor. Hindawi Publishing Corporation 2012 2012-12-23 /pmc/articles/PMC3540709/ /pubmed/23320180 http://dx.doi.org/10.1155/2012/410781 Text en Copyright © 2012 Kenya Kamimura et al. https://creativecommons.org/licenses/by/3.0/ This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Review Article
Kamimura, Kenya
Nomoto, Minoru
Aoyagi, Yutaka
Hepatic Angiomyolipoma: Diagnostic Findings and Management
title Hepatic Angiomyolipoma: Diagnostic Findings and Management
title_full Hepatic Angiomyolipoma: Diagnostic Findings and Management
title_fullStr Hepatic Angiomyolipoma: Diagnostic Findings and Management
title_full_unstemmed Hepatic Angiomyolipoma: Diagnostic Findings and Management
title_short Hepatic Angiomyolipoma: Diagnostic Findings and Management
title_sort hepatic angiomyolipoma: diagnostic findings and management
topic Review Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3540709/
https://www.ncbi.nlm.nih.gov/pubmed/23320180
http://dx.doi.org/10.1155/2012/410781
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