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MiR-145 reduces ADAM17 expression and inhibits in vitro migration and invasion of glioma cells
MicroRNAs are important regulators of gene expression and have been suggested to play a key role in tumorigenesis. In this study, we show that miR-145 is significantly downregulated in glioma cell lines compared to normal brain tissue and negatively regulates tumorigenesis. Restoration of miR-145 in...
Autores principales: | LU, YONG, CHOPP, MICHAEL, ZHENG, XUGUANG, KATAKOWSKI, MARK, BULLER, BENJAMIN, JIANG, FENG |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
D.A. Spandidos
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3540808/ https://www.ncbi.nlm.nih.gov/pubmed/23076445 http://dx.doi.org/10.3892/or.2012.2084 |
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