A review of the potential therapeutic role of statins in the treatment of Alzheimer’s disease: current research and opinion

Alzheimer’s disease is one of the most prevalent neurodegenerative disorders. However, there is no current treatment, which definitively influences disease progression over a sustained period. Numerous studies linking an increase in serum cholesterol, mainly during midlife, with the pathogenic proce...

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Detalles Bibliográficos
Autores principales: Sánchez-Ferro, Álvaro, Benito-León, Julián, Mitchell, Alex J, Bermejo-Pareja, Félix
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove Medical Press 2013
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3540910/
https://www.ncbi.nlm.nih.gov/pubmed/23319866
http://dx.doi.org/10.2147/NDT.S29105
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author Sánchez-Ferro, Álvaro
Benito-León, Julián
Mitchell, Alex J
Bermejo-Pareja, Félix
author_facet Sánchez-Ferro, Álvaro
Benito-León, Julián
Mitchell, Alex J
Bermejo-Pareja, Félix
author_sort Sánchez-Ferro, Álvaro
collection PubMed
description Alzheimer’s disease is one of the most prevalent neurodegenerative disorders. However, there is no current treatment, which definitively influences disease progression over a sustained period. Numerous studies linking an increase in serum cholesterol, mainly during midlife, with the pathogenic process of Alzheimer’s disease have been published. Therefore, the role of statins as a therapy in this disorder may be of great interest. The aim of the present review is to summarize of the role of statins in the treatment of Alzheimer’s disease.
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spelling pubmed-35409102013-01-14 A review of the potential therapeutic role of statins in the treatment of Alzheimer’s disease: current research and opinion Sánchez-Ferro, Álvaro Benito-León, Julián Mitchell, Alex J Bermejo-Pareja, Félix Neuropsychiatr Dis Treat Review Alzheimer’s disease is one of the most prevalent neurodegenerative disorders. However, there is no current treatment, which definitively influences disease progression over a sustained period. Numerous studies linking an increase in serum cholesterol, mainly during midlife, with the pathogenic process of Alzheimer’s disease have been published. Therefore, the role of statins as a therapy in this disorder may be of great interest. The aim of the present review is to summarize of the role of statins in the treatment of Alzheimer’s disease. Dove Medical Press 2013 2013-01-04 /pmc/articles/PMC3540910/ /pubmed/23319866 http://dx.doi.org/10.2147/NDT.S29105 Text en © 2013 Sánchez-Ferro et al, publisher and licensee Dove Medical Press Ltd. This is an Open Access article which permits unrestricted noncommercial use, provided the original work is properly cited.
spellingShingle Review
Sánchez-Ferro, Álvaro
Benito-León, Julián
Mitchell, Alex J
Bermejo-Pareja, Félix
A review of the potential therapeutic role of statins in the treatment of Alzheimer’s disease: current research and opinion
title A review of the potential therapeutic role of statins in the treatment of Alzheimer’s disease: current research and opinion
title_full A review of the potential therapeutic role of statins in the treatment of Alzheimer’s disease: current research and opinion
title_fullStr A review of the potential therapeutic role of statins in the treatment of Alzheimer’s disease: current research and opinion
title_full_unstemmed A review of the potential therapeutic role of statins in the treatment of Alzheimer’s disease: current research and opinion
title_short A review of the potential therapeutic role of statins in the treatment of Alzheimer’s disease: current research and opinion
title_sort review of the potential therapeutic role of statins in the treatment of alzheimer’s disease: current research and opinion
topic Review
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3540910/
https://www.ncbi.nlm.nih.gov/pubmed/23319866
http://dx.doi.org/10.2147/NDT.S29105
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