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Sphingosine 1-phosphate receptors and sphingosine kinase 1: novel biomarkers for clinical prognosis in breast, prostate, and hematological cancers

There is substantial evidence for a role in cancer of the bioactive lipid sphingosine 1-phosphate (S1P), the enzyme sphingosine kinase 1 (that catalyses S1P formation) and S1P-specific G protein-coupled receptors. This perspective highlights recent findings demonstrating that sphingosine kinase 1 an...

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Detalles Bibliográficos
Autores principales:	Pyne, Susan, Edwards, Joanne, Ohotski, Jan, Pyne, Nigel J.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2012
Materias:	Oncology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3540928/ https://www.ncbi.nlm.nih.gov/pubmed/23316473 http://dx.doi.org/10.3389/fonc.2012.00168

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